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SNI Seminar Series: Eckart Gundelfinger
Knowledge of how chemical synapses are formed and how signal transfer between nerve cells occurs is a prerequisite for being able to one day completely understand the workings of the human brain. Gundelfinger’s insights gained by investigating the synaptic signal transfer are considered to be groundbreaking. He was the first scientist to identify and characterize the two „giant proteins“ called „Bassoon“ and „Piccolo,“ which play a decisive role in synapse formation. In his seminar he will talk about new insights on how components of the extracellular matrix that form so-called perineuronal nets around neuronal somata and synaptic sites influence synaptic transmission and plasticity in the CNS. |